IRC | Independent Review Committee

Independent imaging review for decisive endpoints.

EClinCloud IRC unifies image upload and reader workflows on one standardized, GxP-aligned platform — paired with seasoned reader expertise across oncology, CNS, ophthalmology, and beyond — for trial endpoints that stand up to scrutiny.

SponsorsCROsSites / Imaging DepartmentsReview Committees / Readers
ECC IRC · live workspaceLIVE
Blinded read · Case 042Independent review
286Cases
94%Read complete
8Adjudication
DICOM · SERIES 04
Reader 01Complete
Reader 02Complete
AdjudicatorReviewing
Reader identities remain blinded
01

One-stop independent review

A self-developed platform unifies image upload and reading, with controlled progress, traceable results, and a medical team following through on reader turnaround and quality.

02

Deep therapeutic expertise

Seasoned readers across oncology and non-oncology areas — ophthalmology, CNS, cardiovascular, dermatology, respiratory, endocrine — bring expert judgment to endpoint assessment.

03

Proven fast deployment

Deployed in 6 weeks for a cardiovascular program, standardizing 30+ cardiovascular measurements across echo, cardiac MRI, and more.

How it works

01
Stage 1

Design the review

Configure the independent assessment system around the trial endpoints, standardizing read criteria and workflow.

02
Stage 2

Stand up the committee

Independent review committee and reader management, matched with senior experts in the relevant therapeutic area.

03
Stage 3

Upload and QC images

Sites upload images through the platform, with standardized workflows safeguarding acquisition and data quality.

04
Stage 4

Read independently

Expert readers assess on the unified platform while the medical team tracks turnaround and quality throughout.

05
Stage 5

Deliver traceable results

Assessment outcomes are delivered with full traceability — with endpoint adjudication committee management available as well.

Core capabilities

Unified review platform

  • Self-developed system integrating image upload and reading
  • Standardized, GxP-aligned independent review management
  • Built for single-site and multicenter trials
  • Controlled progress with traceable results

Independent assessment services

  • Third-party assessment system and configuration services
  • Independent medical image reading services
  • Review committee and independent reader management
  • Endpoint adjudication committee management

Therapeutic coverage

  • Oncology reading systems and services
  • Non-oncology: ophthalmology, CNS, cardiovascular, dermatology, respiratory, endocrine
  • Senior expert resources across therapeutic areas

Quality assurance

  • A medical team tracking reader turnaround end to end
  • Core team experience across oncology and non-oncology indications
  • 30+ standardized cardiovascular measurements in practice

Supporting services: independent assessment

IRC is not paired with the standard implementation package. Its supporting services are the independent assessment services around endpoint review, delivered by EClinCloud's IRC service and medical teams:

  • Third-party assessment system and configuration services
  • Independent medical image reading services
  • Review committee and independent reader management
  • Endpoint adjudication committee management
Talk to us about independent review →

Connected by design

⇄ EDC
Endpoint assessments interoperate with the study database on one platform.
→ CTMS
Reading progress feeds the trial management view for full control.
← Site imaging
Multicenter images uploaded and quality-controlled through the platform.
← eLearning
Review-related training delivered online with a traceable record.

Frequently asked

Which therapeutic areas do you cover?
Reading systems and independent review services span oncology and non-oncology areas — ophthalmology, CNS, cardiovascular, dermatology, respiratory, and endocrine — with senior experts matched to each.
Who are the readers, and how is quality assured?
EClinCloud maintains IRC service teams and a deep reader network across therapeutic areas, with a medical team following each project through to safeguard turnaround and quality.
How long does deployment take?
A cardiovascular program was deployed in 6 weeks; actual timelines depend on the review design and project complexity, and are confirmed during evaluation.
How does the platform address compliance?
The platform delivers standardized, GxP-aligned independent review management with controlled progress and traceable results. Detailed compliance information is available during evaluation.

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